Short answer: yes it is.  Web visitors are tuning out from ad banners. And what happens? Those who have learnt how to make web banners simply ramp up the “volume” of the banners making them more garish, more flashing, more LOUD. And this makes people tune out banners even more, even using Adblock because they’ve had enough.

The answer isn’t to get louder when someone’s refusing to listen.  It’s to engage them.  Eyes do wander so they will see your banner if it’s not the usual fare. Engage in their desires and needs - be subtle.  Stand out from the other ad banners by using some humour which pays a compliment to the visitor (as it assumes they “get” the joke) - complimenting the visitor in subtle ways is a great way to increase your click through rate.